Berberis Formula (90 capsules) by Genestra

Combination of berberine extracts from natural plant sources

• Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as dyspepsia, and as a mild laxative

• Includes goldenseal root extract, barberry root and stem extract, barberry root bark, Oregon grape root extract, and Oregon grape root

Berberis Formula is a blend of barberry, goldenseal and Oregon grape extracts that are traditionally used in Herbal Medicine to help maintain gastrointestinal health. The main bioactive ingredient in these extracts is berberine.  Recent research demonstrates that berberine inhibits bacterial attachment to the gastric mucosa. Berberine also mediates the transport of ions and water across intestinal epithelial cells. It helps maintain the balance between electrolytes and water, resulting in an anti-diarrheal effect. Berberine can increase the expression of the Na+; H+ exchanger and aquaporin, which help enhance the absorption of sodium and water, respectively. Berberine also promotes proper intestinal epithelial tight junction formation, and decreases the permeability of these cells to promote appropriate gastrointestinal barrier function.5 During low contractile states, berberine stimulates the jejunum through the activation of muscarinic receptors, resulting in increased intestinal motility, and a mild laxative effect.

Suggested Use:
Take 1 capsule 2 times daily with meals or as recommended by your healthcare practitioner. May take up to 1 week to produce beneficial effects.

Each Capsule Contains:
Barberry (Berberis vulgaris) Root Bark Extract (4:1) …. 200 mg (800 mg Dried Equivalent)
Oregon Grape … 200mg
(Mahonia aquifolium) Root Extract (4:1) (Mahonia aquifolium) (4:1) (800 mg Dried Equivalent)
Goldenseal … 50mg
(Hydrastis canadensis) Root Std. Extract (10:1) (5% Alkaloids) (10:1) (5 % dalcalodes) (500 mg Dried Equivalent)
Barberry … 25mg
(Berberis vulgaris) (Root Bark)
Oregon Grape … 25mg
(Mahonia aquifolium) (Root)

Non-Medicinal Ingredients: Hypromellose, cellulose, silica.

Vegan.

Risk Information: Do not use if you are pregnant or breastfeeding. Do not exceed the recommended dose. Consult your healthcare practitioner prior to use if you have a kidney disorder, blood pressure problems, heart or respiratory condition. Avoid taking with alcohol, other medications or natural health products with sedative properties. Stop use and consult your healthcare practitioner if the following symptoms occur: nausea, vomiting, drop in blood pressure or difficulty breathing. Consult your healthcare practitioner if symptoms persist or worsen. High dosages of berberine can depress respiration, stimulate intestinal smooth muscle and reduce bronchial constriction. Keep out of the reach of children. Use only if safety seal is intact. Store in a cool, dry place. Keep out of the reach of children. Use only if safety seal is intact. Store in a cool, dry place.